Enabling the Next Generation of Drug Delivery Through Implantable Medical Devices
(Room 309)
15 Oct 18
11:10 AM
-
12:00 PM
Tracks:
Case Study Sessions, Market Segment Open Meeting, Pre-Expo Conference: Advanced Textiles
The medical device industry has undergone significant evolution over the past several years—and drug delivery is moving to the forefront. With the rapid adoption of drug-eluting stents, the medical industry has recognized the value that drug delivery coupled with a medical device can bring to patient care. Enabling the controlled-release of pharmaceutical and biological agents within the body directly to the internal sites where they are needed has the potential to revolutionize spinal cord repair, nerve generation, tumor remediation and many more applications.
However, the types of drugs and therapeutic agents able to be successfully loaded to fibers for incorporation into implantable medical devices have traditionally been limited by the manufacturing process itself—typically melt extrusion. Now, the emergence of alternative extrusion methods that occur at room temperature is enabling drug-loading of a wider range of pharmaceutical and biological agents than ever before possible for use in biodegradable implantable devices for localized drug delivery within the body. The incorporation of these drug-loaded fibers into new or existing medical devices can result in faster healing, improved patient compliance, and lower negative outcomes at relatively low cost.
This presentation will explore the latest advancements in extrusion technology which are enabling the next generation of drug delivery. It will also explore some of the medical applications that stand to be most significantly impacted by this technological advancement.
1. Drug delivery from fiber allows for slow sustained release, avoids high toxic levels, may be site specific and aids patient compliance.
2. Novel extrusion methods for drug loading enable the broadest range of drugs for use in biodegradable implantable devices.
3. Drug delivery from fiber can be used in a variety of medical applications including: advanced drug delivery, nerve regeneration, tissue engineering and medical textiles.
4. D