Moderator: Joseph S. Butler, PhD, FRCS (Tr & Orth)
104. Zoledronic acid decreases infection burden in mouse model of spine implant Infection
Chad Ishmael, MD1; Peter P. Hsiue, MD2; Zachary Burke, MD3; Kellyn R. Hori, BS3; Justo Caballero, BS3; Vishal Hegde, MD2; Clark J. Chen, BS1; Brian K. Zukotynski, BS3; Sam I. Uweh, BS3; Cristina Villalpando, BS3; Nicolas A. Cevallos, BS4; Nicole Truong, BS5; Douglas M. Dang3; Alexandra Stavrakis, MD6; Nicholas Bernthal, MD7
1University of California Los Angeles, Los Angeles, CA, US; 2UCLA Department of Orthopaedic Surgery, Los Angeles, CA, US; 3Los Angeles, CA, US; 4Bernthal Lab, Los Angeles, CA, US; 5Orthopaedic Hospital Research Center, Los Angeles, CA, US; 6Santa Monica, CA, US; 7UCLA, Santa Monica, CA, US
FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs.
105. Sex-based differential response in rhBMP-2-mediated spinal fusion in vivo
Mitchell Hallman, BA1; Jonathan T. Yamaguchi, BS2; David J. Ellenbogen, BA1; Allison Greene, BS3; Vivek P. Shah, BS4; Soyeon Jeong, MS5 Joseph G. Lyons, BS1; Mark A. Plantz, BS5; Tejas Nandurkar, MS1; Chawon Yun, PhD5; Wellington K. Hsu, MD5; Erin L. Hsu, PhD5
1Chicago, IL, US; 2Hsu Lab, Simpson Querrey Institute, Chicago, IL, US; 3NU FSM, Dept of Orthopaedic Surgery, Chicago, IL, US; 4Robert H. Lurie Medical Research Center of Northwestern University, Chicago, IL, US; 5Northwestern University, Chicago, IL, US
FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs.
106. Subclinical propionibacterium acnes infection estimation in the Intervertebral disc (SPInE-ID)
Nelson Astur Neto, MD, MSc1; Marcelo Wajchenberg, PhD2; Michel Kanas, MD3; Alberto O. Gotfryd Sr., PhD4; Mario Lenza, MD, PhD5; Delio E. Martins, MD3
1Instituto Astur, Sao Paulo, SP, SP, Brazil; 2Universidade Federal de Sao Paulo, Sao Paulo, SP, Brazil; 3São Paulo, Brazil; 4Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil; 5Hospital Israelita Albert Einstein, Sao Paulo, Sao Paulo, Brazil
FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs.
107. Internal deformations in human intervertebral discs under axial compression: A 9.4T MRI study
Saman Tavana, MEng1; Jessica Prior, MEng2; Nicoleta Baxan, PhD1; Ulrich Hansen, PhD3; Spyros Masouros, PhD4; Brett A. Freedman, MD5; Nic Newell, PhD, Meng1
1Imperial College London, London, United Kingdom; 2GSK, Worthing, United Kingdom; 3London, United Kingdom; 4Exhibition Road, London, London, United Kingdom; 5Mayo Clinic, Rochester, MN, US
FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs.
108. Posterior bone-graft options and success in single-level circumferential lumbar fusions
Glenn R. Buttermann, MD
Midwest Spine Institute LLC, Stillwater, MN, US
FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs.
109. An investigational study of a dual-layer, chorion-free amnion patch as a protective barrier following lumbar laminectomy in a sheep model
Bryan W. Cunningham, PhD1; Breanna Seiber, BS2; Jessica Riggleman, BS2; Margaret R. Van Horn, PhD2; Archana Bhat, PhD2
1MedStar Union Memorial Hospital, Baltimore, MD, US; 2Globus Medical, Inc., Audubon, PA, US
FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs.
110. Use of a novel allograft in single-level posterolateral lumbar spine fusion surgery: one-year clinical and radiographic results from a prospective multicenter study with comparison to reported results for ICBG
Joshua Bunch, MD1; Douglas C. Burton, MD1; Scott D. Daffner, MD2; Howard S. An, MD3
1University of Kansas Medical Center, Kansas City, KS, US; 2West Virginia University School of Medicine, Morgantown, WV, US; 3Rush University Medical Center, Department of Orthopedic Surgery, Chicago, IL, US
FDA Device/Drug Status: OSTEOAMP (Approved for this indication)
Discussion